NMN Prime 500mg – NMN Supplement, 60 Capsules – Nicotinamide Mononucleotide · Health Canada Licensed

One 500 mg capsule a day for adults 18 and older — that's the dose on the NMN Prime label. Human studies have used between 250 mg and 1,250 mg a day, but don't take more than the label dose unless your healthcare practitioner advises it.

NMN works gradually, so judge it over 8 to 12 weeks, not days. In a 60-day randomized trial, blood NAD⁺ levels had already risen by day 30 (Yi et al., 2023). One bottle of NMN Prime lasts 60 days.

Either is fine. The NMN Prime label has no food requirement, so take it at whatever point in your day you'll remember. If supplements tend to upset your stomach, take it with a meal.

Most people take NMN in the morning as part of their routine, but the label doesn't specify a time. Taking one capsule at the same time each day matters more than the hour. Our NMN timing guide covers the research.

Many people take their capsule alongside their morning coffee, and the NMN Prime label carries no caffeine warning. If you take prescription medication, check with your pharmacist before adding any supplement.

NMN is a precursor your cells convert into NAD⁺ in a single step. Oral NAD⁺ is a much larger molecule that's thought to be largely broken down during digestion, which is why most human research uses precursors like NMN or NR. See the comparison table above, or read NMN vs NAD⁺.

In human trials, NMN was well tolerated at daily doses from 250 mg up to 1,250 mg, with no serious adverse events reported (Fukamizu et al., 2022; Yi et al., 2023). Consult a healthcare practitioner before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medication. Stop taking it if you have an adverse reaction. More in our NMN side effects guide.

Yes. NMN Prime is licensed by Health Canada as a natural health product under NPN 80139252. When you buy NMN in Canada, check the label for an 8-digit NPN — it means Health Canada has assessed the product for safety, efficacy and quality.

The best NMN supplement in Canada is one you can verify. Check for three things: a Health Canada NPN on the label, a recent third-party Certificate of Analysis, and a clear amount of NMN per capsule. NMN Prime 500mg has all three: it is licensed under NPN 80139252, made in Canada in a GMP-certified facility and tested by Canadian Analytical Laboratories.

Costco and other large retailers have carried NMN supplements, but stock changes by store and season. Wherever you buy, compare the NPN, the NMN per capsule, the third-party testing and the price per 500 mg — not just the sticker price. NMN Prime ships directly to you with free shipping across Canada and the U.S. Read our Costco NMN buyer’s guide.

Harvard geneticist Dr. David Sinclair has said publicly that he takes NMN, and his lab's research on NAD⁺ helped bring NMN to wide attention. Zeroo Health isn't affiliated with or endorsed by Dr. Sinclair. Read David Sinclair and NMN.

60 days. Each bottle holds 60 capsules and the label dose is 1 capsule a day. For six months at a lower price per bottle, choose the 3-Bottle Value Pack.

Each vegetarian capsule contains 500 mg of nicotinamide mononucleotide (NMN). Non-medicinal ingredients: hypromellose (the capsule), microcrystalline cellulose and magnesium stearate. It contains no artificial preservatives, sweeteners or colours, and no wheat, dairy, yeast or gluten.

NMN Prime is for adults 18 and older. Because NAD⁺ levels tend to decline with age, many people start in midlife, but there's no single right age. Our guide to NAD⁺ levels by age explains what the research shows.